Tuesday, December 1, 2020

Carnitine for Fatigue, Depression and Erectile Dysfunction


For the millions of men in this country who suffer with fatigue, depression or erectile dysfunction, I’ve got some exciting news for you.


In the current edition of the journal, Urology, researchers reported on a study with the nutrient carnitine. 120 patients were randomized to receive oral testosterone, a combination of propionyl-L-carnitine 2 grams a day, along with acetyl L-carnitine 2 grams a day, or placebo.

Participants in the study ranged between the ages of 60-74 and complained of decreased sexual drive, erectile difficulty, depressed mood, irritability, difficulty with concentration, and fatigue. The study was blinded and continued for six months.

At the end of the study, it was found that both carnitine and testosterone treatment improved penile blood flow, thereby improving erectile function, along with sexual desire.

Testosterone, however, did not improve scores for orgasm or general sexual well-being at any point, whereas the carnitine group had improvement in both orgasm and general sexual well-being at both three months and at the end of the six-month study.

Carnitine was superior to testosterone in overall erectile function. Both carnitine and testosterone also improved depression scores, although carnitine was superior to testosterone. Fatigue was likewise improved in both groups.

As one negative effect, the men taking testosterone developed enlargement of their prostates, which did not occur in the carnitine-treated group. Although both testosterone and carnitine improved symptoms of male aging, there was overall superior benefit to carnitine with no real side effects.

Carnitine is an interesting nutrient. It has vitamin-like qualities. It is considered essential in helping to transport fatty acids into mitochondria (the power plants of the cells). A deficiency in carnitine can therefore result in an overall reduction in energy production by the cells.

It is well-known that individuals can become carnitine-deficient for a number of reasons. L-carnitine, aside from being an incredible anti-aging nutrient, also has shown benefit for multiple medical conditions, including cardiovascular disease such as angina and congestive heart failure, liver and kidney disease, obstructive lung disease, and many others. L-carnitine has actually even shown benefit in AIDS patients.

Although it is unusual to see physicians prescribing vitamins in the hospital, I routinely notice that the kidney specialists prescribe carnitine for their patients, since the kidney is a major site of carnitine synthesis.


Supplement companies have realized the importance of L-carnitine over the last several years. If you have follow formulations, you may have noticed that there have been more and more acetyl L-carnitine to supplements because of the incredible benefits that it provides. Stand-alone acetyl L-carnitine or L-carnitine fumerate 500 mg supplements are also good.

There is another excellent anti-aging nutrient that I’ve written about many times in the past called alpha lipoic acid. There was an incredible study published in a prestigious medical journal which demonstrated that aging rats, when given a combination of both acetyl L-carnitine and alpha lipoic acid, began performing more like younger rats.

When these animals were autopsied, they actually found regeneration of parts of the brain. These nutrients were literally predicted to be anti-aging compounds.

It’s never too late to turn back the clock with anti-aging nutrients. Always keep improving! Until next time.

References & Further Reading:

Writes in the lane of nutrition and natural treatment.

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