Invisible energy from the sun penetrates the atmosphere to endanger everyone on the planet, including humans, animals and aquatic life. Sunburn is an acute overexposure to sunlight which contains UV light, also known as ultraviolet light/radiation or UVR. The event causes inflammation in the skin and produces a red tint, pain, and oftentimes peeling of the damaged skin. This toxic event can be seen as overdosing, as some sunlight exposure is beneficial. When the body’s protective pigment, melanin, is insufficient to handle the sunlight or other UV light, first and second degree burns occur with unsightly and painful results.
How does sunburn happen?
Sunburn is a sneaky ailment, as the pain which would warn you, develops hours after the event. This delayed-onset pain is part of a spectrum of symptoms which can appear 2-48 hours after the sun exposure event. Sunburn is often noticed by other people before being felt by the victim. By that time, the condition is irreversible and the damage has been done. Sunburn is a common ailment and inspires concern in others.
Acute inflammation is triggered by sunburn, causing a release of fatty acids which metabolize and regulate stages of the inflammation, until resolution. Resolution happens when small molecules called photolyases attempt to heal the damage. The UV light causes damage to the DNA, and if the photolyase enzyme cannot make repairs, the cells will die in a process known as apoptosis, and a radiation, not thermal, burn occurs.
Repairs are attempted at an atomic level, as the molecule attempts to break chemical bonds caused by UV light. Photolyase injects a proton and electron into the injured strand of DNA and can heal damage in a few billionths of a second. Irretrievably broken cells go through cell death, and cell death causes the pain commonly associated with sunburn.
Pain is Warning
The body’s intelligent design acts to save your life by impacting you where it hurts. Pain alerts you to wake up and pay attention. In the short-term, the body gives you pain in order that you might remove yourself from the light source, or make an escape The pain further encodes in your brain, or sets a neural pathway to interrupt and remind you of the pain, so that you might avoid overexposure to sunlight in the future. The most difficult time, most painful time will likely be between 12-36 hours after the event.
Not Usually Life Threatening
Sunburn is an event, not a disease or a chronic condition, but it’s not an event to take lightly. Serious reactions include dehydration, signs of shock and extreme exhaustion. Calling a health care provider immediately is the safest course of action after overexposure to solar radiation. Most people, however, do not seek medical attention, but use over-the-counter medications and home remedies.
Sunlight-Positive and Negative
Life on earth is made possible with sunlight, which activates many processes including photosynthesis for plants and trees. In turn, plant life creates oxygen that all life uses. Energy from sunlight triggers a chemical process to produce oxygen for the atmosphere, for organisms to breathe and indirectly to produce food. Vitamin D synthesis in our skin is triggered by sunlight. Bone health in children and adults is contingent on adequate Vitamin D production. Other health conditions benefit from the influence of vitamin D.
Measuring the actual intensity of the sun provides data on the risks. At higher doses, UV rays cause normal sunburn, compromise the immune system, damage DNA and lead to cancer. Seasonal changes, weather variations and ozone depletion affect the UV index. In the U.S., every day in mid-afternoon, the National Weather Service publishes the forecast for the next day at the EPA, Environmental Protection Agency website. You can sign up for email alerts including UV alerts which warn of significantly high risks, or see the range of risks on a scale from 1 (low) to 11+ (extremely high). Most countries and weather websites list the UV index as part of the weather forecast.
UVA vs. UVB
Long-wave rays, UVA and short-wave rays, UVB come from our six billion year old sun. UVC rays also emanate from the sun but are mostly absorbed by the atmosphere. 95% of the rays reaching the surface are UVA rays, which is why science has mostly focused on the long wave rays. However, the other 5% of rays, the UVB rays, are under increased scrutiny by scientists and prevention/treatment recommendations may change.
Both kinds of rays are harmful, so make sure to get a sunscreen with an SPF of 15 or higher, that blocks or neutralizes UVA and UVB rays. UVB rays target the top layers of skin and are the main culprit in sunburn. UVA rays go into the deeper layers of the skin and can trigger allergic reactions. Be sure to use the recommended amount of sunblock and reapply as needed.
Sunlight Positive Effects
Tanning, evolutionarily speaking, served as a useful adaptation to ultraviolet radiation. Tanning, or the darkening of skin pigment, is seen when societies migrate from low level UV areas to high UV areas. Skin darkening serves to defend against microorganisms, stop overproduction of Vitamin D, protect against skin cancer, shield blood vessels and sweat glands, and adapt to environmental temperatures.
Sun avoidance is not recommended as solar rays trigger a cascade of beneficial events. Precursor chemicals are activated in the presence of sunlight to produce vitamin D, which plays a protective role against cancer.
Dosing or regulating the amount of sunlight becomes important, as does adjusting for differences in geographical location, latitude, and altitude.
Solar rays are also associated with positive mood and behavior. Serotonin levels are lowest in the winter during reduced sunlight availability. Serotonin is called the happy molecule. This neurotransmitter not only affects mood, but also memory, learning, mate search, as well as appetite and movement. Sun therapy is accepted for depressive disorders, insomnia, and seasonal affective disorders.
Sunlight Negative Effects
Negative consequences occur when overdosing on sunlight. Sunburn, poisoning, illness and even death are the result of miscalculating proper sun exposure. Physicians say that intentional tanning, or a calculated browning of the skin, seen as desirable by many, is not normal and a myth. Premature aging of the skin is the result of unprotected sun exposure.
Comfort is compromised by sunburn. A painful, itchy and irritated feeling is likely to result from an acute overdose of sunlight or UV radiation (UVR). Comfort and a feeling of safety with other people will decline as a result of hypervigilance to not being touched. Clothing may rub on the skin and cause pain. Bed sheets may cause friction while trying to sleep. Almost all activities will be uncomfortable as skin may feel tight and painful with any kind of movement. Appearance or presentation to others will suffer. The red tint to the skin is unnatural and noticed immediately by others. Peeling skin is unsightly and unpleasant to others. The aesthetic or beauty reasons for sun seeking or tanning become invalid when the opposite result is reached.
Skin damage is permanent. When the skin burns, free iron is released inviting free radical formation. Free radicals are molecules which cause cell damage and aging. They proceed to trigger a cascade of negative cellular events like knocking down dominoes, especially when interacting with DNA.
Skin cancer: The 3 major forms of skin cancer are cutaneous malignant melanoma, basal cell carcinoma; and squamous cell carcinoma. Thought to be the result of reactions between free radicals and DNA, half of all cancers are skin cancers caused directly and indirectly by sun exposure, especially as child.
Melanoma, the most deadly or lethal form of skin cancer is one of the few cancers increasing in incidence and becoming a world-wide health burden. The risk for invasive malignant melanoma is 1 in 59. In the 1930’s, it used to be 1 in 1,500, meaning for every fifteen hundred people back then, one person was likely to develop melanoma. Now, one person in every fifty-nine people will suffer and likely die from melanoma, and rates are expected to increase over the next twenty years.
- Development of melanoma is directly related to a lifetime of
sunburns and sun overexposure. A molecular pathway, not a specific gene,
is mutated by UV light and triggers melanoma development. Sunburn is
the most significant risk factor for melanoma development but other
factors do exist:
- first-degree relative with melanoma
- blistering sunburns
- atypical mole syndrome
- UV exposure at tanning salons
Appearance – damaged or dead skin cells do not look good. Premature aging from photoaged skin is characterized by loss of collagen and elasticity. Wrinkled, leathery, patchy, and discolored skin is the result of long-term UVR exposure.
Reproduction – Overexposure to sunlight can cause a reduction in folate levels. Folate is a B vitamin which aids in cell growth and impacts sperm quality and reproductive success in pregnancy.
- 3rd degree burns – all layers of the skin are damaged. Nerves and tissue in the skin are damaged and skin looks white or burnt. No pain may be felt due to nerve damage.
- 2nd-degree burns – very painful, produces blisters, red, swollen or splotchy skin.
- 1st degree burns – red, painful, swollen and may peel after a few days.
Symptoms are temporary but can cause real pain and disability.
- dehydration – the process of removal of water from the body. May have dry mouth, dizziness, trouble enunciating words or thinking clearly.
- dizziness – an unsteady or lightheaded feeling.
- pink or red skin – known as erythema.
- sensitive skin – sensation of warmth, able to feel the slightest touch, air or wind, hyper responsive to physical stimuli including perspiration, clothing, and touch.
- blisters – skin is raised or elevated with fluid or air inside a bulbous form, blisters burst easily and can trigger infection.
- itching – pruritus, or an irritating sensation provoking a need to scratch or claw at the skin in hopes of pain relief.
- peeling skin – flaking of outermost skin due to cell death.
- pain – acute discomfort, anguish, emotional distress, skin tenderness.
- difficulty sleeping – pain and discomfort may cause problems going to sleep and waking in the middle of night.
Serious reactions also known as sun poisoning can make one feel very ill.
- nausea – physical disgust in a state preceding vomiting
- vomiting – forced or uncontrollable ejection of stomach contents though the mouth.
- fever – elevation of body temperature, frequently caused by infection.
- chills – shivering, goose bumps, clammy and moist skin and/or pale skin.
- headache – pain in the head or neck.
- skin infections – bacterial, viral or fungal.
- major blisters – blisters which cover a significant portion of the body. 5-15 % blistering needs medical attention.
- fast pulse or breathing – rapid respiratory rate.
- extreme thirst – sudden, insatiable desire to drink liquids.
Life Threatening Symptoms
In 1999, in Arizona, USA an elderly Alzheimer’s patient was left alone outside on a patio for hours and suffered burns on the exposed parts of her body. She subsequently died from the sunburn. Deaths from sun overexposure stem from the skin’s failure to protect against infection, preserve fluids and control body temperature. Much depends on other complicating factors like heart, kidney or lung disease. A person’s age, general health, and ability to heal are factors as well.
Diagnosis and Treatment
Seeking advice and treatment is a worthwhile effort after a sunburn event. Your physician or health practitioner will begin with questions about your current symptoms, conduct a physical exam and make a visual inspection of your skin and order diagnostic tests if needed. Your sun exposure habits and sunburn history may be part of the evaluation. Common questions may include:
- When did the sunburn occur?
- Where did exposure occur?
- Did you use a sunblock or sunscreen? What type of sunblock and what strength level?
- Do you get sunburn often?
- Which parts of the body were burned?
- What medicines do you take? – Some medications, treatments or topical lotions can make sunburn worse such as the antibiotic doxycycline.
- What else are you feeling?
- Rate the pain on a scale of 1 to 5, five being the worst.
- Do you have itching or blisters?
- Do you have a history of sunburns?
- Does your family have a history of sunburns?
Photo-testing – not commonly ordered because the test is usually negative in sunburn cases. This procedure tests for the least amount or the minimal doses of sunlight, UVA and UVB, which causes a erythemal or redness reaction.
Photo patch – sunlight reacts with some substances or allergens to produce a skin disorder, which this procedure tests for.
Photoprovocation – tests for differing reactions to UVA/UVB radiation. One arm is dosed with UVA, with the equivalent of a half hour of sun, three days in a row. The other arm is dosed with the UVB.
Skin Biopsy – invasive sampling of the skin rarely used in sunburn cases.
Other tests – not commonly used for sunburn, but may be ordered for complications of sunburn or for diagnosing a sun-related problem:
- Blood Tests, Blood Count, Urine/Fecal
No treatment can reverse sun damage but pain and discomfort can be managed. Time is the best healer as NSAIDs, antioxidents, oral and topical corticosteroids, and antihistimines have little effect on recovery time.
Pain Management – pain arrives on your doorstep as cells die, within 2-48 hours after sun overexposure. Pain medication may be prescribed during this time, and as needed afterwards. Medications like analgesics, topical anesthetics, corticosteroids, and anti-inflammatory agents like ibuprofen are commonly recommended.
Remedies – Compresses applied before the application of lotion is the accepted treatment. A compress of aluminum acetate, an astringent with antiseptic properties, can dry and heal. Aluminum acetate is commercially available. A cold damp washcloth, cool shower or bath may help. Some people add milk to the cold compress, and vinegar or oatmeal to the bath.
How to make a cold compress: Fill a bowl with water and add ice cubes. Let the ice chill the water for a few minutes. Take out the ice cubes. Add desired compress agent like milk, aluminum acetate, vinegar, peppermint oil, or green tea. Immerse a washcloth into the water. Take out and wring out until dry. Apply to affected area until compress is not cold anymore. Repeat as needed.
Keeping the skin moisturized by applying bland emollients, also known as lotion, can encourage skin healing. A bland emollient is skin lubricant or moisturizing lotion. Lotions do not add moisture to the skin. They trap moisture in the skin. Hypo allergenic products are preferred, fragrance and dye free.
Best moisture trappers are oils like petroleum jelly, however some physicians feel it also traps unwanted heat as well. Creams are second best and then lotions. Aloe Vera, a common home treatment, shows no advantage in clinical studies. Apply after bathing, each time skin is washed and periodically through the day.
Nutrition – drinking lots of water moisturizes the skin and speeds healing. Nutritional therapies include eating foods with high water content like celery. Anti-inflammatory foods such as salmon, berries and greens could jump start the immune system.
Time to endure/heal – sunburn can take about 2 weeks to subside.
- 3rd degree burns take a long time to heal.
- 2nd-degree burns take 2 to 3 weeks healing time.
- 1st-degree burns can heal in 3 to 6 days.
Comfort – avoid touch, ask spouse to sleep elsewhere, choose clothing and bed sheets which minimize friction. Avoid wool and nylon, and choose cotton fabrics instead. Cornstarch or talcum powder sprinkled on bed sheets may help.
Behaviors to avoid – breaking or puncturing blisters or peeling and removing skin can expose you to the possibility of infections. Avoid lotions with alcohol, which dries the skin. Avoid products with benzocaine unless directed by a physician.
Apply antibiotic ointment to blisters and cover with a sterile bandage.
Hospitalization – to monitor vital signs and administer IV fluids. Children with 10% blistering and adults with 15% to 25% blistering may need hospitalization.
- Avoid the sun during peak sun ray intensity of 10 am and 4 pm.
- Stay in the shade of trees, buildings or umbrellas.
- Check the UV Index before going out.
- Take extra precautions with children, elderly and disabled.
- Hats – Wear any kind of hat to protect your head and eyes, but a wide brimmed hat is better.
- Clothing – tightly woven, long sleeved pants and shirts, any kind of covering at all to protect yourself. SPF treated clothing and swimwear is available.
- Sunglasses – UV protection, blocks rays and protects eyes.
- Laundry detergent – agents like bis-ethylhexyloxyphenol methoxyphenyl triazine improve fabric’s ability to block UV rays.
Sunblock acts as a filter, barrier, reflector or absorber for UVA and UVB sunlight.Sunscreen’s effectiveness in the lab and packaged for production, uses a measurement of 2 mg cm. Meaning, the product must be applied in a certain amount to be protective. However, most people do not put that much on and typically do not reapply, so the SPF rating is really just a beginning. Sunbathers and workers must use a good amount and reapply when needed.
- Lip balm/stick – lips are a sensitive area that deserve sunscreen or SPF, simple zinc oxide works well.
- Lotions – Apply generous amounts of sunscreen with a sun protection factor (SPF) of at least 15 “broad spectrum” to block both UVA and UVB rays. Pay attention to your face, nose, ears, and shoulders. The higher the SPF, the greater the protection.
- Apply sunscreen 30 minutes prior to sun exposure to allow penetration.
- Re-apply every 2 hours while you are outdoors, and after swimming or washing.
SPF Labeling and Claims
Some have pointed to the insufficiency of SPF, Sun Protective Factor labeling. Some physicians and scientists feel that sunscreen companies use emotional and inaccurate messages to promote sunscreen use. Terms such as multi spectrum or broad spectrum may not be meaningful. The Food and Drug Administration in the U.S. wants consumers to know that not all products are equal.
Studies have shown that people do not use enough of the product on their bodies which makes the sunscreen only partially effective. Sunscreen labeling using qualitative measures is recommended. Under new regulations only products that protect against both UVA and UVB rays, with a SPF of 15 or higher, will be allowed to be called, “broad spectrum.” The FDA recommends reading the label from front to back to reduce the effect of misleading claims.
Types of SPF Products/Applications
- Oils, Sprays, Lotions, Creams, Gels, Butters, Pastes, Sticks – topically applied, form a protective barrier over the skin. Personal preference determines the type used, as all offer some protection with correct application. The FDA requires that manufacturers not make claims of immediate protection upon application, or identify their products as “sunblocks”, “waterproof” or “sweatproof.”
- Pills – the active ingredient in sunblock pills is a plant native to Central America, Polypodium leucotomos (cabbage palm fern). The biological compound provides antioxidant effects, acting as a cleanser of sun damage. Some studies have shown reduced burning when taking the pill as a prophylactic, or preventative. Study results are mixed however, and manufacturer’s claims may not be supported. Children, pregnant or nursing women should not take the pill.
- Vending Machines – some high risk areas, heavily populated with sun seekers, are using vending machines to apply sunscreen. Users step into a booth and are sprayed by multiple nozzles all over the body. This type of application promotes use because of the novelty, ease of application and price. Other types of vending machines, distribute packets of sunscreen for regular application.
About twenty ingredients are approved by the U.S. FDA for use in sunscreens. Chemical and organic compounds like zinc oxide, titanium dioxide, avobenzone, ecamsule, oxybenzone, are included in lotions and sprays to dissipate, deflect or absorb UV energy by forming a shield on the skin. Inorganic, physical, insoluble nanoparticles can also be found in sunscreens and reflect UV rays away from the body. Zinc oxide formulas are recommended for children.
The Parent and Pediatrician Role in Childhood Prevention
Since preventing childhood sunburn is the key to avoiding cancer, the pediatrician and the parent play a vital role in education and prevention. Some studies have found that poor sun knowledge and behavior on the part of the parent is likely to be associated with sunburn in the children. When parents improve their behaviors, children get fewer sunburns and decrease their risk of cancer.
Vigilance on the part of the family doctor or children’s doctor is recommended. The pediatrician can modify the attitudes of the parents and the children. Physicians should be aware of all the major environmental issues affecting people, including chemicals in the house and other toxic substances and events like sunburn. Outdoor sports are popular activities for kids and a prime area for physicians to intervene and recommend sun safety.
Social and Behavioral Therapy
Researchers tried a novel behavior intervention with middle school students in Massachusetts. Some students were in the experiment group and others were in a control group. Both groups received a lecture on sun exposure. The experiment group received a photo of their face taken with a special filter to show UV damage, while the control group did not receive a picture.
After two months those who had received a picture reported fewer incidents of sunburn than those who did not receive a picture. Viewing the photograph appeared to have a deterrent effect on the students. Most participants agreed that it was a helpful tool and kept their picture.
After six months the effects seemed to have lessened with more sunburn reports, but still less than the control group. Impressionable teenagers can choose positive behaviors when presented with personal evidence and visual demonstration of the negative consequences of their behavior.
Marie-France Demierre, a professor of dermatology and medicine at Boston University School of Medicine, believes every child should routinely get a UV photograph of their face. A specially designed UV filter is placed over the camera lens. A wave-length of light, 400 nanometers, penetrates deeper into the skin than does visible light, recording absorption and reflection of long-wave UV light by the person.
Dermatologists can refer patients for UV photography. A reputable photographer in your community may be able to document you or your child’s skin condition photographically. Home photographers can use black and white film, as no advantage is found for color film. Some photographers use the Kodak T-Max 400 black and white film, standard flash, and a Kodak Wratten 18A UV filter.
Outdoor workers, especially water instructors and lifeguards, have a high risk of sunburn and overexposure to UV radiation. This type of outdoor work, near water, increases the risk of sunburn and these occupations are normally filled with young, white females in high school and college. This age group consistently has issues with sun protection skills. Most all of these workers have experienced sunburn and half of them have a history of severe sunburn.
Researchers at Rollins School of Public Health, Emory University, Atlanta, found few workplace interventions conducted in the lifesaving occupation, where it’s most needed. Lower sunburn incidents were reported in environments which did foster sun safety programs. More importantly, researchers concluded that peers or co-workers have a positive influence in developing healthy sun habits.
Motivating people to avoid ultraviolet exposure is another means to prevent sunburn and associated ultraviolet overdosing. Health advocates call for health promotion techniques targeting differences in genders and educating the whole family, with support from school and work systems.
Sociodemographics – People and Places
The sun’s rays are strongest closer to the tropics (lower latitude) and during the hours of 10:00 a.m. to 4:00 p.m. Higher altitudes or mountainous regions can be more dangerous for sun exposure. Persons in northern latitudes, like Scandinavia, produce less vitamin D than persons in countries like Australia.
Everyone has varying reactions to the sun depending on factors like the amount of melanin produced in the body. Melanin protects against the sun. Lighter skin people have less melanin-producing cells, melanocytes. Melanocyte cells, in the bottom layer of the skin, are stimulated by UVB rays to produce melanin.
Millions of people suffer from sunburn every year. Infants, children, and people with fair skin are more likely to get sunburn. Studies show mixed results for sunburn prevalence between genders. Both male and female adults experience sunburn.
Dark skin is also susceptible to harmful effects of the sun. A dark skinned person may endure sun exposure for hours where a light skinned person could get burned within 15 minutes. T.B. Fitzpatrick, a dermatologist at Harvard, developed The Fitzpatrick Scale in 1975 to classify UV reactions in different skin types. Types range from Type 1 which never tans and always burns, to the opposite Type 6 which never burns and always tans.
Most children have sunburn every year, and a third of all children have three or more sunburn events each year. 25% of sun exposure occurs before 18 years of age. Pediatricians and researchers report poor effectiveness in protecting children from sun damage despite public health initiatives.
Some countries, like Australia, have a culture revolving around outdoor pursuits, sun-seeking and tanning. These attitudes are pervasive and influence lifestyle, social norms, customs, peer groups and business activities.
People who are more likely to use sunscreen are female, have a friend that uses sunscreen, have parents that insist on sunscreen, and know the times of safe sun exposure.
Staying in shaded areas, wearing sunscreen, hats and glasses are recommended during these pleasure pursuits. Also, being aware of the UV Index may be helpful. Postponing an activity may be wise if the risk is too high. Some recreational pursuits and locations where sunburn is likely:
- Gardening, boating, sports, beach, lake, backyard, fishing, skiing, and golfing.
Strategies for policies and practices in the workplace regarding sun exposure are not common. In the absence of structured guidance from management, an individual may have to use common sense in occupations where sun exposure is guaranteed. Typical jobs where overdosing on sunlight is likely:
- Lifeguard, Construction, Landscaping, Trash Collector, Street Police, Crossing Guards, Road Flagger.
Related Sun Problems
Photodermatoses – contact with a plant substance which makes that area light sensitive or some metabolic disorders may cause this related problem. Primarily UVA radiation causes this hypersensitivity. Sunburn is not a photodermatose, as sunburn can happen to anyone and is mostly caused by the UVB spectrum. One type of photodermatose is when one develops eczema in reaction to sunlight. One in 10 people react this way to the sun.
In some people, rubbing a lime on the skin exposes the skin to a reaction from sunlight, with symptoms of redness, swelling, blistering, and itching like poison ivy. Figs, celery, parsley, fruits, plants, and oil of bergamot, found in fragrances, can cause a photosensitizing reaction when exposed to the skin. Treatment consists of avoidance behaviors, topical ointments, cool compresses, antihistimines, steroids and other medications. Negative consequences include permanent discoloration of the skin.
Photo-aging – called external aging, as the inflammation from long term sunbathing makes fine blood vessels and wrinkles appear more pronounced.
Solar Keratosis – scaly skin, also called actinic keratosis, can sometimes develop from patches of pink skin into large patches of brown skin and may be pre-cancerous.
Sun Addicts – “tanorexics” or sun worshippers that become addicted, exhibit similar symptoms as alcoholics, may refuse intervention, have repeated exposure and may cause concern in others. Women are three times as likely as men to become addicted. Addicts report the first thought when waking is desire to tan and guilt over not being able to stop tanning. Education about the dangers of overexposure does not deter behavior and sun addicts may become annoyed by interventions.
FAQs and Myths
- Sunscreen is applied before cosmetic makeup. True. Sunscreen always goes first, before any other topical application, with the possible exception of acne medication.
- Truck drivers can get sun damage only on the arm that hangs out of the window. True.
- Effects of water magnify the sun. True. Reflections from water, sand, or snow can intensify the sun’s burning rays.
- Sun lamps and tanning beds can cause severe sunburn. True. 16% of boys and 33% of teenage girls have visited a tanning salon at least once. Protective eye goggles are recommended and sometimes mandatory.
- People with freckles sunburn faster. True. Sometimes the freckles can fuse together and become bigger.
- Can fish and animals get sunburn? Yes. Koi fish and whales have been diagnosed with sunburn. Dogs, cats, reptiles, and farm animals are susceptible to overexposure to the sun.
- UVA, unlike UVB, can penetrate window glass. True. UVA can penetrate loosely woven clothing and car windows.
- I can’t get a sunburn on a cloudy day. False.
- Sunscreen is a modern product. False. Zinc oxide was used by WW II sailors to deflect sunlight
Anti-photoaging agents are any compound or drug that interferes with the chain reaction initiated by sun overexposure, immunosuppression, free radical and DNA damage.
Honeybush, a tea extract, mangiferin, a compound found in mangos and hesperidin, a flavonoid in citrus fruits, can protect the skin from UVR. Researchers believe that these extracts may reduce oxidative damage, inflammation and possibly regulate cell signaling.
Researchers are looking for a mechanism, stimulant or compound to increase the production of a protein called caspase-14, which plays a role in skin moisture. Skin absent of caspase-14 has diminished skin barrier function. Added to sunblock lotion, this compound could offer protection against UVR.
Massive amounts of iron are released after a sunburn event, inviting free radical damage. Drugs called chelators can transport iron away from the cells. Chelators bind to iron and carry it from the body. Difficulties lie in finding chelators that don’t become toxic for the cell. Researchers are finding solutions in chelators added to sunscreen that only become active when exposed to UV radiation.