Monday, September 28, 2020

Supplementation to Reverse Memory Loss


As a neurologist I read with great interest an article just published in the prestigious journal Proceedings of the National Academy of Science. In this study, aging rats were fed two special nutrients, acetyl-L-carnitine and alpha lipoic acid.

Dietary supplementation with these two nutrients improved memory including spatial memory (assessed by a water maze) along with temporal memory. Even more exciting, electron microscopic studies of the hippocampus of these animals showed that these two nutrients reversed age-associated mitochondrial structural damage. It was concluded that these results suggested feeding acetyl-L-carnitine and alpha lipoic acid to all rats improves performance and memory tasks by lowering oxidative damage and improving mitochondrial function.

Conventional treatment has been a failure

Unfortunately, traditional treatment for dementia/Alzheimer’s is rather pathetic. There are three drugs currently available in the United States. All of these drugs work in a similar matter to raise acetylcholine (a neurotransmitter) levels in the brain. The benefits are very small and not long lasting, with the risk of side effects. Memory function clearly involves more than one neurotransmitter. To date, researchers have been unable to develop any pharmaceutical products to deal with the complex issue of memory loss.

I am, therefore, excited to offer not only my patients, but everyone concerned with the possibility of memory loss a natural alternative.


Look for a supplement that contains numerous antioxidants, and phytonutrients, specifically geared for improving memory and cognitive function. Included in the formulation is 300 mg of alpha lipoic acid and 1000 mg of acetyl-L carnitine. Additionally, the supplement should contain 300 mg of phosphatidylserine.

There are over 30 studies proving the safety and benefits of phosphatidylserine in patients with memory loss and impaired cognitive function. A good supplement contains a nutrient that is quite popular in Europe known as vinpocetine. This unique nutrient has been well studied and is an excellent cerebral metabolic enhancer to improve cognitive function. Further, supplements should contain optimal levels of B vitamins required for healthy neurological function.

The amount and form of B12 utilized in this product is so significant that it could potentially achieve blood levels similar to those achieved from an injection of B12. Studies indicate this level and form of B12 may actually repair oxidative damage in the central nervous system. It should also contain 120 mg of standardized gingko biloba, 800 mg of a natural blend of mixed tocopherals (vitamin E), along with numerous other vitamins, minerals and antioxidants.

If you prefer to take these nutrients individually, you can find supplements for these too. These include 300 mg capsules of alpha lipoic acid, 500 mg capsules of acetyl-L carnitine, 100 mg softgels of phosphatidylserine and a powerful B-Complex product.

References & Further Reading:


  1. Lynette Armstrong

    Supplementing your diet with brain healthy nutrients may help preserve memory and maintain sound cognitive function as you age. These neuronutrients, which fuel brain cells and promote healthy blood flow to the brain, include phosphatidylserine, ginkgo biloba, coenzyme Q10, alpha lipoic acid, acetyl-L-carnitine, resveratrol and omega-3 fatty acids. It is important, however, to know which forms, amounts and combinations of these nutrients will provide the most benefit to the health of your brain for years to come.

Writes in the lane of nutrition and natural treatment.

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